pentobarbital will lower the level or result of voriconazole by impacting hepatic enzyme CYP2C9/ten metabolism. Minimal/Importance Mysterious.pentobarbital will lower the level or outcome of doxorubicin liposomal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.Elderly or debilitated clients may react to barbiturates